Promoters as tumour suppressors: MYC vs. PVT1 for gene expression

The collection of genes expressed, when they are expressed and how much they are expressed are what give a cell its personality. Consequently, regulating gene expression is very important and there are many molecular mechanisms through which it is achieved. Understanding these mechanisms provides a clearer picture to deciphering what goes wrong in cells when […]

Read More Promoters as tumour suppressors: MYC vs. PVT1 for gene expression

CRISPR just got snappy…

Biologists have a way of coming up with cool abbreviations; ChIP(Chromatin immunoprecipitation), DAPPER (DAtabase for Protein-Protein intERactions), ERGIC (ER–Golgi intermediate compartment) , TESCO (testis specific enhancer of Sox9 core element), but one of my personal favourites is CRISPR* – clustered regularly interspersed short palindromic repeats. *And as Hermione might say, it’s not crispaar, it’s, crisper. […]

Read More CRISPR just got snappy…