Stress eating to death: autophagy is key to tumour suppression on replicative crisis

Wondering “how I am going to afford that?”, breaking something valuable or moments before an important talk/interview are just a few moments where one can become stressed. However, stress to a cell is very different. Have you ever stressed about whether a protein was folded correctly, if there are breaks in your DNA, or whether […]

Read More Stress eating to death: autophagy is key to tumour suppression on replicative crisis

Promoters as tumour suppressors: MYC vs. PVT1 for gene expression

The collection of genes expressed, when they are expressed and how much they are expressed are what give a cell its personality. Consequently, regulating gene expression is very important and there are many molecular mechanisms through which it is achieved. Understanding these mechanisms provides a clearer picture to deciphering what goes wrong in cells when […]

Read More Promoters as tumour suppressors: MYC vs. PVT1 for gene expression

The sex chromosomes – Y is there a Y and the great X-scape

Throughout evolution many mechanisms to determine sex have arisen. Whilst in many species sex is determined genetically, environmental factors such as temperature or even social variables such as size can influence the fate of an organism’s sex. Other species change sex throughout their lifetime. In humans, sex is determined by the sex chromosomes present in […]

Read More The sex chromosomes – Y is there a Y and the great X-scape

CARs designed to tackle cancer

CARs designed to tackle cancer Every so often you have a ‘wow’ moment in life. This may be from seeing one of the wonders of the world or witnessing a great performance on stage. For me, my common ‘wow’ moments are of the ‘Wow, how come I have only just discovered this when others have […]

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