Techniques to track and follow proteins inside living cells have vastly improved over the last decade, however comparable methods for tracking RNA have lagged behind. This is primarily due to the lack of intrinsically fluorescent RNA to match the expertise of the protein kind, like GFP (green fluorescent protein). Corn is one of the latest […]Read More Imaging RNA in a cell with Corn
Bacteria are everywhere. Well, pretty much everywhere. On that door handle, your bed, the air to the bottom of the ocean and the trillion inside your own bodies! Their pure diversity provides an exceedingly large study source to improve our biochemical and physiological understanding of cellular processes, but especially the effect bacteria can play on […]Read More A bacterial aphrodisiac?
When people say their house have an infestation this is usually associated with something bad, say, an infestation of ants, wasps or rats for example. However, currently attracted to the flowering ivy in my backyard is a confetti of red admiral butterflies, painted with splashes of white and stripes of orange over a velvety dark […]Read More Butterfly wing patterns just got CRISPR
CARs designed to tackle cancer Every so often you have a ‘wow’ moment in life. This may be from seeing one of the wonders of the world or witnessing a great performance on stage. For me, my common ‘wow’ moments are of the ‘Wow, how come I have only just discovered this when others have […]Read More CARs designed to tackle cancer
2 meters doesn’t sound like much. However, this is the same length of DNA that is compacted inside the nucleus of each cell. Now, considering that nuclei have a diameter a fraction of a mm and nuclear proteins need to be included as well, this raises the important question, how does DNA fit? This apparent […]Read More Time to re-write the textbooks? How DNA is really packed inside the nucleus.
Many of you are probably familiar with the tree of life that Charles Darwin used when explaining his theory of evolution, but maybe not so much with his own family tree. It would not at all be surprising to see that Darwin had cousins but neither would it to see that one was Francis Galton. […]Read More Darwin’s cousin – the man who made a beauty map of Britain
Protein Profile #1: RNA polymerase II Much like the variety of outfits we wear to follow the latest fashion trend, cells mediate their own styles through changing their gene expression patterns to fit with their surrounding environment. Gene expression is an important daily event for a cell which results in the production of proteins but […]Read More Get transcribed in style: The CTD that everyone’s talking about
Not only is this title a painful reminder of a mistake I made in my exam this year, but simply wrong since centromeres will still be included in discussion! So, just to clarify, centrosomes are the organelles from which microtubules (MTs)* arise from, whilst centromeres are regions on chromosomes that attach to MTs via the […]Read More Centrosomes, not centromeres, and error-correcting kinetochores
Biologists have a way of coming up with cool abbreviations; ChIP(Chromatin immunoprecipitation), DAPPER (DAtabase for Protein-Protein intERactions), ERGIC (ER–Golgi intermediate compartment) , TESCO (testis specific enhancer of Sox9 core element), but one of my personal favourites is CRISPR* – clustered regularly interspersed short palindromic repeats. *And as Hermione might say, it’s not crispaar, it’s, crisper. […]Read More CRISPR just got snappy…
This is my first blog. For those who have come here to find out my innermost secrets and thoughts, you have come to the wrong place. The aim of this blog is to educate, entertain and elucidate on a variety of science topics that I find interesting, recent research and general science-related topics. As a […]Read More A honest introduction to my blog