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Loop it like cohesin

Chromatin, the combination of DNA and protein that resides within our nuclei, takes on a variety of forms. These forms vary depending on the type of cell, the stage of a cell’s cycle and environmental conditions. Techniques to pinpoint regions of chromatin contacts within a nucleus have provided great insight into nuclear organisation and the […]

Read More Loop it like cohesin

Exploiting the endogenous: An ADAR way to edit RNA by only adding oligos

Genome editing, with its permanent modification of DNA, necessitates that the editing is conducted both safely and efficiently. An alternative mechanism, that could be both reversible and dose dependent in terms of percentage editing, is to edit at the RNA stage. However, this precise RNA editing faces similar safety and efficiency requirements if it is […]

Read More Exploiting the endogenous: An ADAR way to edit RNA by only adding oligos